Bedside Rounds

Alvarado score for acute appendicitis

The Alvarado score (MANTRELS) combines eight findings to estimate the likelihood of acute appendicitis and guide imaging and surgical referral.

What goes into the Alvarado score

  • Migration of pain to the right lower quadrant (+1)
  • Anorexia (+1)
  • Nausea or vomiting (+1)
  • Right lower quadrant tenderness (+2)
  • Rebound tenderness (+1)
  • Temperature ≥ 37.3 °C (99.1 °F) (+1)
  • WBC > 10,000/µL (+2)
  • Left shift (neutrophils > 75%) (+1)

How to interpret the result

  • ≤ 3: appendicitis unlikely
  • 4–6: equivocal; image
  • 7–10: appendicitis likely; surgical consultation

Clinical pearls

  • Best for ruling out; high scores still over-call appendicitis, especially in women.
  • CT is the usual test in adults; ultrasound first in pregnancy and young patients.
  • CODA (2020): antibiotics are a reasonable alternative for selected uncomplicated cases, but about 3 in 10 need appendectomy by 90 days.

Evidence

  1. Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med. 1986;15:557-564.

Related workups

Related calculators

For education only. Check the inputs and the population the score was validated in before acting on it. Not a substitute for clinical judgment.