What goes into the BISAP score
- BUN > 25 mg/dL (+1)
- Impaired mental status (GCS < 15) (+1)
- SIRS (≥ 2 criteria) (+1)
- Age > 60 (+1)
- Pleural effusion on imaging (+1)
How to interpret the result
- 0–2: lower risk (mortality < 2%)
- 3–5: higher risk (mortality about 5–20%)
Clinical pearls
- Severity is defined by persistent organ failure > 48 hours (revised Atlanta), not by any single score.
- WATERFALL (2022): moderate goal-directed fluids were safer than aggressive resuscitation.
- Start early oral feeding as tolerated.
Evidence
- Wu BU, et al. The early prediction of mortality in acute pancreatitis: a large population-based study. Gut. 2008;57:1698-1703.
Related workups
Related calculators
For education only. Check the inputs and the population the score was validated in before acting on it. Not a substitute for clinical judgment.