Bedside Rounds

eGFR (CKD-EPI 2021) calculator

Estimates glomerular filtration rate using the CKD-EPI 2021 creatinine equation, which removed the race coefficient and is recommended by the NKF-ASN Task Force for US laboratories.

What goes into the eGFR (CKD-EPI 2021)

  • Creatinine (mg/dL)
  • Age (years)
  • Sex: Male; Female

How to interpret the result

  • G1 ≥ 90 (with other kidney damage), G2 60–89, G3a 45–59, G3b 30–44, G4 15–29, G5 < 15 mL/min/1.73 m²

Clinical pearls

  • Only valid when creatinine is stable: not in AKI.
  • Add cystatin C when muscle mass is unusual or the decision is high-stakes.

Evidence

  1. Inker LA, et al. New creatinine- and cystatin C-based equations to estimate GFR without race. N Engl J Med. 2021;385:1737-1749.

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For education only. Check the inputs and the population the score was validated in before acting on it. Not a substitute for clinical judgment.