Bedside Rounds

Corticosteroid dose conversion

Converts between equivalent anti-inflammatory doses of common glucocorticoids.

What goes into the Steroid conversion

  • From: Prednisone; Prednisolone; Methylprednisolone; Hydrocortisone; Dexamethasone
  • Dose (mg)

How to interpret the result

  • Equivalent doses: prednisone 5 mg = prednisolone 5 mg = methylprednisolone 4 mg = hydrocortisone 20 mg = dexamethasone 0.75 mg

Clinical pearls

  • Hydrocortisone has meaningful mineralocorticoid activity; dexamethasone has none.
  • Durations of action differ: dexamethasone is long-acting, hydrocortisone short-acting.
  • Consider stress-dose steroids and adrenal suppression after more than about 3 weeks of therapy.

Evidence

  1. Liu D, et al. A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy Asthma Clin Immunol. 2013;9:30.

Related workups

Related calculators

For education only. Check the inputs and the population the score was validated in before acting on it. Not a substitute for clinical judgment.